Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: About Acetaminophen Overdose Liver injury induced by paracetamol and challenges associated with intentional and unintentional use Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health Tylenol depletes glutathione levels Early life acetaminophen exposure, glutathione S transferase genes, and development of adolescent asthma in a high risk birth cohort Journal of Allergy and Clinical Immunology